Angiofibroma is a descriptive term for a group of lesions with different clinical presentations but with the same histopathology. Mean age at diagnosis is 14 years may regress in late teens but may persist into adulthood rare in patients older than 25 years. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. Angiofibroma juvenil nasofaringeo scielo cuba infomed. Infact hippocrates goes on to describe a polyp in the nose which weeped blood. Also known as fibrous papule common benign fibrohistiocytic tumor, usually on the face of middle aged persons and often on the nose some have postulated this lesion to be a hamartoma composed of perifollicular or interfollicular connective tissue and a hair follicular epithelial component j cutan pathol 2009. Cunningham, in comprehensive pediatric hospital medicine, 2007. Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns. Pdf it is presented a case of juvenile nasopharyngeal angiofibroma in a patient with this pathology, from the clicial practice no. There are several distinct clinical forms of angiofibroma which share identical histopathology fibrous papule. Review article nasopharyngeal angiofibroma ashutosh hota. Juvenile nasopharyngeal angiofibroma is a rare, highly luiz a cr, romualdo s lt, fava a. Angiofibroma of nasopharynx is a highly vascular, rare and benign tumor, with a high a. Nasal obstruction may become total, with adenoidtype speech.
Vessels are thinwalled, lack elastic fibers, have absent or incomplete smooth muscle, and vary in appearance from stellate or staghorn to barely conspicuous because of stromal compression. Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor of the nasopharynx that arises from the superior margin of the sphenopalatine foramen and grows in the back of the nasal cavity. The tumors are frequently located in the posterolateral wall of the nasal cavity. Angiofibroma of nasopharynx is a highly vascular, rare and benign tumor, with a high a incidence of recurrence and local invasity which nature always defied the. Nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. The endoscopic resection is best indicated for small tumors confined to the nasopharynx, nasal cavity, ethmoid and sphenoid, and in some cases, tumors with extension into the pterygopalatine fossa 4. Pdf juvenile nasopharyngeal angiofibroma with intradural. The nci dictionary of cancer terms features 8,568 terms related to cancer and medicine we offer a widget that you can add to your website to let users look up cancerrelated terms. Though it is a benign tumor, it is locally invasive and can invade the nose, cheek, orbit. In 1906 chareau revived the interest in the study of juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma jna is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. Introduction nasopharyngeal angiofibroma is a histologically and biologically benign tumor with aggressive behavior due to its location and associated symptoms including significant epistaxis and nasal obstruction since then, several cases have been reported, all showing that endoscopic resection resulted in lower morbidity during the early stages of disease in this study, we.
Tuberous sclerosis affects both the nervous system and the skin neurocutaneous and may also produce other skin lesions including shagreen spots, ash. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that predominantly occurs in adolescent males, the average age of occurence being 15. These lesions include fibrous papule, facial angiofibroma, pearly penile papule, adenoma sebaceum, periungual fibroma, and koenens tumor. Retrospective descriptive study of patients diagnosed with juvenile nasopharyngeal angiofibroma admitted in the. Juvenile nasopharyngeal angiofibroma with intradural extension article pdf available in brazilian journal of otorhinolaryngology 775. Angiofibromas cause a domeshaped mass in the superficial dermis figure 1. This is a pdf file of an unedited manuscript that has been accepted for publication. The jna juvenile nasopharyngeal angiofibroma is a rare neoplasm, of benign histology, that affects almost exclusively male sex adolescent. Juvenile nasopharyngeal angiofibroma is a rare, highly luiz a cr, romualdo s lt, fava a s. Angiofibromas are small, reddish brown or even fleshcolored, smooth, shiny, 0. Juvenile nasopharyngeal angiofibroma jna onset most commonly is in the second decade.
Juvenile nasopharyngeal angiofibroma has been documented since the time of hippocrates 4 bc. Angiofibroma, juvenile fibroma, angiofibroma or nasopharyngeal hemangioma, it. Generally, an angiofibroma presents as 1 to 5 mm skincolored to erythematous domeshape papule on the face. Juvenile nasopharyngeal angiofibroma naj is a tumor with.
It most commonly affects adolescent males because it is a hormonesensitive tumor. Angiofibroma definition of angiofibroma by medical. Its incidence practically aims to him at being exclusive of men in ages next to the puberty. Although a histopathologically benign tumor of vascular origin, jna behaves locally invasive and. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for. Histologically, angiofibromas are characterized by fibrosis of the dermis and blood vessels. The overlying epidermis is uninvolved but may be atrophic. Pdf angiofibroma juvenil nasofaringeo researchgate. Epidemiology juvenile nasopharyngeal angiofibromas. Iiprofessor in the department of head and neck surgery.
It is an aggressive neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium. Angiofibroma nasofaringeo juvenil linkedin slideshare. These red erythematous elevated skin lesions papules are tumors madeup of fibrous tissue angiofibroma and occur with tuberous sclerosis. Currently, surgery appears to be the best treatment of the naj.
Angiofibroma is a pink, firm, 1 to 2mm domeshaped papule most commonly located over the nasal bridge and cheeks fig. Juvenile nasopharyngeal angiofibroma jna is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the. Ppt journal juvenile nasopharynx angiofibroma free download as powerpoint presentation. Angiofibroma juvenil pdf juvenile nasopharyngeal angiofibromas jna are a rare benign but locally aggressive vascular tumor.
The typical patient is an adolescent male with a clinical history of recurrent epistaxis and nasal obstruction. Definition of angiofibroma national cancer institute. The typical symptoms of juvenile nasopharyngeal angiofibroma are chronic. It is the most common benign tumor of the nasopharnyx but only accounts for less than 0. Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. Retrospective, descriptive study conducted after approval from the ethics committee of the federal university of sergipe protocol methods we analyzed 20 patients with nasopharyngeal angiofibroma who underwent surgery in the otolaryngology service between and nasofarngro tumour of the respiratory system.
Angiofibroma nasofaring juvenile free download as pdf file. Acessos cirurgicos no angiofibroma nasofaringeo juvenil relato. Ppt journal juvenile nasopharynx angiofibroma radiation. It most commonly affects adolescent males and may grow into fissures of the.
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